Non-invasive medical devices attract investment By Buzzy Gordon JERUSALEM (January 4, 2001) - As medical, life-sciences, and biotechnology start-ups get ready to become the next wave of hi-tech interest for investors, replacing the slumping Internet sector, one of the hottest new niches in the medical devices market comprises non-invasive medical procedures - or "health without needles." Just yesterday, Jerusalem Global Ventures (JGV) announced an investment of $3.6 million in Petah Tikva-based Glucon, a seed-stage company founded in June of this year that is developing a non-invasive technique for the measurement of blood elements and components. This process would facilitate home-based, continuous monitoring of glucose for diabetics, putting an end to painful and annoying pinpricks to draw blood. JGV, a $200m. group of seed-focused venture-capital funds, made the investment through the its Neve Ilan-based InnoMed fund, which specializes in life sciences and medical devices. JGV's chairman is Dr. Shlomo Kalish, while the InnoMed managing partner is Dr. Dalia Megiddo. According to Megiddo, "Glucon's new product, an innovative blood-glucose monitor, will eliminate the discomfort of needles and the inconvenience of fluid collection while supplying accurate, real-time glucose-monitoring results for patients and physicians alike. "InnoMed, true to the venture model, provides Glucon's entrepreneurs with initial financing and continuing support to achieve the company's goals. With InnoMed's 'Start-Up Acceleration' services backing Glucon's extensive technology know-how, Glucon is now well-positioned to reach its ambitious milestones." This latest development follows InnoMed's recent $2.6m. investment in Inventis, a local start-up that has developed a device for the non-invasive treatment of male impotence. Also in the news this week, OrSense, a start-up medical device company based in Rehovot, was awarded "Best Abstract Award" for clinical research excellence in the area of non-invasive hemoglobin monitoring at the annual meeting of the American Society of Anesthesia. OrSense's abstract was selected among several thousand which were published at the October conference, taking into consideration the importance of non-invasive hemoglobin in the anesthesia setting, as well as the wide-ranging promise that the research represents for medical practice on the whole. "We are pleased and encouraged at having received such prestigious recognition of our technology, which also has very significant applications in the area of non-invasive measurement of glucose and cholesterol. We are confident and excited by the potential of our technological breakthrough and look forward to expanded clinical trials and regulatory applications during 2001," said OrSense CEO Abe Coriat. "Our proprietary sensor technology is designed to non-invasively measure multiple and vital parameters, such as blood glucose, hemoglobin, cholesterol, and more. Our electro-optical technology performs non-invasive blood measurement by means of a finger probe, vastly decreasing the need to take blood by needle-stick. "We aim to bring to market the first universal platform sensor of its kind, targeting a potential market worth more than $5 billion." OrSense, founded in 1996, is backed financially by local venture-capital firms Star Ventures Capital Management and Tamar Technology Ventures, both of Herzliya. Similarly, other non-invasive and minimally invasive technologies have received corporate and financial boosts. Only two weeks ago, Haifa-based Elbit Systems announced the formation of MediGuide, a spinoff company that will focus on intra-body navigation applications enabling minimal invasive procedures with great accuracy. Discount Capital Markets has already invested $1m. in the company, which plans to raise $5m. The recently launched Koor Medabiotech Fund made one of its first investments in Simbionics, which is developing simulation tools for non-invasive surgery. Itamar Medical, which is pioneering the development of a neurovascular signal that provides a non-invasive way of monitoring the autonomic nervous system, was listed by the prestigious Ramat Gan research firm D&A Hi-Tech Information as one of their top 50 leading private companies in Israel.